Atg4D Polyclonal Antibody

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. ATG4D (autophagy related 4D cysteine peptidase) belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants.

The Atg4D Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Atg4D protein expression in various biological samples. This antibody has been meticulously developed using advanced techniques to ensure exceptional sensitivity and specificity.

Atg4D, a member of the autophagy-related protein family, plays a crucial role in the autophagy process by cleaving the C-terminal region of Atg8 proteins. By targeting Atg4D, this polyclonal antibody enables researchers to investigate the intricate mechanisms underlying autophagy regulation and its implications in various physiological and pathological conditions.

The Atg4D Polyclonal Antibody exhibits outstanding performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its high affinity and selectivity guarantee accurate and reproducible results, making it an indispensable tool for scientists studying autophagy-related processes.

This antibody has been rigorously validated using multiple experimental approaches, ensuring its reliability and consistency. It exhibits minimal cross-reactivity with other related proteins, further enhancing its specificity. Additionally, it demonstrates excellent stability and long shelf life, allowing for prolonged usage without compromising its performance.

The Atg4D Polyclonal Antibody is supplied in a convenient and user-friendly format, making it suitable for both experienced researchers and newcomers in the field. It is provided in a liquid form, ready for immediate use, eliminating the need for time-consuming reconstitution steps.

In summary, the Atg4D Polyclonal Antibody is a cutting-edge research tool that offers exceptional sensitivity, specificity, and reliability. Its versatility and ease of use make it an invaluable asset for scientists investigating autophagy-related processes and their implications in various biological contexts.