Atm Polyclonal Antibody

The protein encoded by ATM belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.

The Atm Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Atm protein expression in various biological samples. This antibody is produced through a rigorous process, ensuring its exceptional quality and performance.

The Atm Polyclonal Antibody exhibits a high affinity towards Atm protein, enabling precise and accurate detection in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its exceptional sensitivity allows for the detection of even low levels of Atm protein expression, making it an invaluable tool for researchers working in the field of DNA damage response and repair.

This antibody is manufactured using advanced techniques and undergoes stringent quality control measures to ensure batch-to-batch consistency and reproducibility. It has been extensively validated in various experimental settings, demonstrating its reliability and specificity in detecting Atm protein expression.

The Atm Polyclonal Antibody is supplied in a convenient and ready-to-use format, eliminating the need for time-consuming and complex preparation steps. Its long shelf life and stability make it an ideal choice for long-term storage and repeated use.

In summary, the Atm Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of Atm protein expression. Its exceptional sensitivity, batch-to-batch consistency, and convenience make it an indispensable asset for researchers in the field of DNA damage response and repair.