ATP-citrate synthase Polyclonal Antibody

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for ACLY.

The ATP-citrate synthase Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of ATP-citrate synthase in various biological samples. This antibody is produced through a rigorous process, ensuring its high affinity and specificity towards the target protein.

ATP-citrate synthase is a key enzyme involved in the citrate metabolism pathway, playing a crucial role in cellular energy production and lipid synthesis. Its dysregulation has been implicated in various diseases, making it an important target for research and diagnostic purposes.

This polyclonal antibody is derived from a diverse pool of immunized animals, resulting in a broad range of epitope recognition. It has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

With its exceptional sensitivity and specificity, this antibody enables accurate and reliable detection of ATP-citrate synthase in complex biological samples. Its high-quality formulation ensures minimal background noise and maximum signal intensity, facilitating precise quantification and analysis.

Furthermore, this antibody exhibits excellent reproducibility and stability, allowing for consistent and reliable results across multiple experiments. Its long shelf life and robust performance make it an ideal choice for both academic and industrial research applications.

In summary, the ATP-citrate synthase Polyclonal Antibody is a valuable tool for researchers and clinicians alike, offering reliable and accurate detection of ATP-citrate synthase in various biological samples. Its high specificity, sensitivity, and versatility make it an essential component in studying the role of ATP-citrate synthase in cellular metabolism and disease progression.