ATP5G1 Polyclonal Antibody

ATP5G1 (ATP synthase, H+ transporting, mitochondrial Fo complex subunit C1) encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation.

ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8).

ATP5G1 is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding the same protein have been identified.

The ATP5G1 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of ATP synthase subunit gamma 1 (ATP5G1) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human ATP5G1 protein. The ATP5G1 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence applications.

This antibody is suitable for use in a wide range of research applications, including studies of mitochondrial function, energy metabolism, and cellular respiration. The ATP5G1 Polyclonal Antibody is supplied in a liquid format and is ready to use for research purposes. It is recommended to store this antibody at -20°C for long-term storage and to avoid repeated freeze-thaw cycles. With its high specificity and sensitivity, the ATP5G1 Polyclonal Antibody is an essential tool for researchers studying ATP synthase subunit gamma 1 and related biological processes.