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BT Lab

SKU(재고 관리 코드):BT-AP00747

ATP7A Polyclonal Antibody

ATP7A Polyclonal Antibody

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Ab type

ATP7A (ATPase copper transporting alpha) encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway.

It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in ATP7A are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed.

The ATP7A Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of ATP7A protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human ATP7A protein.

The ATP7A Polyclonal Antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence applications. This antibody is suitable for use in a wide range of research applications, including studies of copper metabolism, Menkes disease, and Wilson's disease. The ATP7A Polyclonal Antibody is supplied as a purified IgG fraction, and is available in various sizes to meet the needs of different research projects.

With its high specificity and sensitivity, the ATP7A Polyclonal Antibody is an essential tool for researchers studying copper transport and related diseases.

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