Atrophin-1 Polyclonal Antibody

Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.

The Atrophin-1 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Atrophin-1 protein expression in various biological samples. This antibody has been meticulously developed using advanced immunization techniques, resulting in a high affinity and exceptional sensitivity towards Atrophin-1.

Atrophin-1, a transcriptional corepressor, plays a crucial role in the regulation of gene expression and is implicated in various cellular processes, including development, differentiation, and neurodegenerative disorders. The Atrophin-1 Polyclonal Antibody recognizes the full-length Atrophin-1 protein as well as its isoforms, ensuring comprehensive detection and analysis.

This antibody exhibits outstanding performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been rigorously validated to provide accurate and reproducible results, making it an ideal choice for both research and diagnostic purposes.

The Atrophin-1 Polyclonal Antibody is manufactured under strict quality control standards, ensuring batch-to-batch consistency and reliability. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation.

With its exceptional specificity, sensitivity, and versatility, the Atrophin-1 Polyclonal Antibody is an indispensable tool for scientists and clinicians working in the fields of molecular biology, neuroscience, and pathology. Experience the unparalleled performance of this antibody and unlock new insights into the intricate mechanisms governed by Atrophin-1.