AZI1 Polyclonal Antibody

AZI1, also known as 5-azacytidine-induced protein 1, is a 1,083 amino acid protein that may play a role in spermatogenesis. AZI1 is most highly expressed in spinal cord, followed by testis, ovary, amygdala, cerebellum and thalamus. Low expression is present in other adult and fetal tissues and specific adult brain regions. AZl1 gene transcription begins in pachytene spermatocytes and expression of the gene is induced in cultivated fibroblasts on treatment with 5-azacytidine, which is known to lead to the demethylation of genomic DNA. The AZI1 gene is conserved in dog, cow, mouse, rat, chicken, and zebrafish, and exists as two alternatively spliced isoforms. AZI1 contains one IQ domain, and the gene that encodes it maps to human chromosome 17q25.3. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

The AZI1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of AZI1 protein expression in various biological samples. This antibody is produced using state-of-the-art techniques, ensuring high affinity and specificity towards AZI1.

AZI1, also known as 5-azacytidine-induced protein 1, is a crucial protein involved in diverse cellular processes, including cell cycle regulation, DNA repair, and apoptosis. Its dysregulation has been implicated in various diseases, making it an important target for research and diagnostic purposes.

The AZI1 Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes endogenous levels of AZI1 protein, enabling accurate quantification and localization studies.

With its superior sensitivity and specificity, this antibody provides researchers with reliable and reproducible results, facilitating a deeper understanding of AZI1's role in cellular processes and disease pathogenesis. Its versatility and robustness make it an invaluable tool for both basic research and clinical applications.

The AZI1 Polyclonal Antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and minimizing experimental variability. It is available in different sizes to accommodate various experimental needs. Each batch is rigorously quality tested to ensure consistent performance and reliability.

In summary, the AZI1 Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of AZI1 protein expression. Its exceptional performance in various applications, combined with its convenience and reliability, makes it an essential asset for researchers and clinicians alike.