BAF53 Polyclonal Antibody

ACTL6A (actin like 6A) encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. ACTL6A encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.

Introducing the BAF53 Polyclonal Antibody, a highly reliable and efficient tool for various research applications. This antibody is meticulously developed using advanced techniques to ensure exceptional specificity and sensitivity, making it an ideal choice for scientists and researchers in the field.

The BAF53 Polyclonal Antibody is designed to target the BAF53 protein, a crucial component of the BAF chromatin remodeling complex. This complex plays a pivotal role in regulating gene expression, DNA repair, and chromatin structure. By specifically recognizing and binding to BAF53, this antibody enables precise investigation and analysis of its functions and interactions within the complex.

With its exceptional affinity and selectivity, the BAF53 Polyclonal Antibody guarantees accurate and reproducible results in a wide range of experimental settings. It is suitable for various techniques, including Western blotting, immunohistochemistry, immunofluorescence, and immunoprecipitation. Its versatility allows for comprehensive exploration of BAF53's involvement in diverse biological processes and disease mechanisms.

This antibody is produced through a rigorous purification process, ensuring high purity and minimal background noise. Its polyclonal nature enhances its sensitivity, enabling detection of even low-abundance BAF53 protein levels. Additionally, it exhibits excellent stability and long shelf life, ensuring consistent performance throughout your research endeavors.

The BAF53 Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is provided in a liquid form, ready for immediate use without the need for reconstitution. Each vial is carefully packaged to maintain its integrity and quality, guaranteeing optimal performance upon arrival.

In summary, the BAF53 Polyclonal Antibody is a superior research tool that offers exceptional specificity, sensitivity, and versatility. Its reliable performance, coupled with its ease of use, makes it an indispensable asset for scientists and researchers seeking to unravel the intricate mechanisms of the BAF chromatin remodeling complex.