Bag-4 Polyclonal Antibody

The protein encoded by BAG4 is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein (BCL2 associated athanogene 4) was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

Introducing the Bag-4 Polyclonal Antibody, a cutting-edge scientific tool meticulously designed to revolutionize research in the field of molecular biology. This high-quality antibody is specifically engineered to target Bag-4, a crucial protein involved in various cellular processes, including apoptosis and cell survival.

Crafted with utmost precision and expertise, the Bag-4 Polyclonal Antibody exhibits exceptional specificity and sensitivity, ensuring accurate and reliable results in a wide range of applications. Its superior affinity towards Bag-4 enables efficient detection and quantification, facilitating comprehensive analysis of Bag-4 expression levels in diverse biological samples.

The Bag-4 Polyclonal Antibody boasts an advanced formulation, meticulously optimized to deliver unparalleled performance. Its exceptional stability and consistency guarantee consistent results, minimizing experimental variability and enhancing reproducibility. With its exceptional signal-to-noise ratio, this antibody enables precise detection even in low abundance samples, empowering researchers to delve deeper into the intricate mechanisms governed by Bag-4.

Furthermore, the Bag-4 Polyclonal Antibody is validated for various techniques, including Western blotting, immunohistochemistry, and immunofluorescence, offering versatility and flexibility to suit diverse experimental requirements. Its compatibility with multiple species, including human, mouse, and rat, further broadens its applicability, facilitating cross-species research and comparative analysis.

In addition to its exceptional performance, the Bag-4 Polyclonal Antibody is manufactured under stringent quality control measures, ensuring utmost purity and reliability. Rigorous testing and validation procedures guarantee batch-to-batch consistency, providing researchers with a dependable tool for their scientific investigations.

Choose the Bag-4 Polyclonal Antibody to unlock new frontiers in molecular biology research. With its unrivaled performance, versatility, and reliability, this antibody is poised to revolutionize the understanding of Bag-4's intricate role in cellular processes, paving the way for groundbreaking discoveries and advancements in the field.