BAI-1 Polyclonal Antibody

Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 (adhesion G protein-coupled receptor B1, ADGRB1) contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas.

The Atg9a Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Atg9a protein in various biological samples. This antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity. The Atg9a Polyclonal Antibody is ideal for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Atg9a protein is a key component of the autophagy pathway, which is responsible for the degradation of cellular components. The Atg9a Polyclonal Antibody is designed to specifically recognize the Atg9a protein, allowing for the accurate detection and quantification of this important protein in various biological samples. This antibody has been extensively validated for its specificity and sensitivity, ensuring reliable and reproducible results.

The Atg9a Polyclonal Antibody is produced using high-quality polyclonal antibodies that have been carefully selected and validated for their specificity and sensitivity. This antibody is supplied in a convenient format, making it easy to use in a wide range of applications. The Atg9a Polyclonal Antibody is an essential tool for researchers studying the autophagy pathway and its role in various biological processes.