BARD1 Polyclonal Antibody

BARD1 encodes a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. This protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. This protein may be the target of oncogenic mutations in breast or ovarian cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for BARD1.

Introducing the BARD1 Polyclonal Antibody, a cutting-edge scientific tool designed to facilitate accurate and efficient detection of BARD1 protein expression. This high-quality antibody is meticulously developed using advanced techniques, ensuring exceptional specificity and sensitivity for a wide range of applications in various research fields.

The BARD1 Polyclonal Antibody is meticulously produced through a rigorous process, starting with the selection of highly specific antigenic peptides. These peptides are then used to immunize animals, followed by purification of the resulting polyclonal antibodies. The resulting product exhibits outstanding affinity towards the BARD1 protein, enabling precise identification and quantification of its expression levels.

With its exceptional specificity, the BARD1 Polyclonal Antibody offers researchers a reliable tool for various applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its versatility allows for the exploration of BARD1 protein expression in diverse biological samples, facilitating comprehensive investigations into its role in cellular processes and disease mechanisms.

The BARD1 Polyclonal Antibody's superior sensitivity ensures accurate detection even in low abundance samples, minimizing false negatives and maximizing data reliability. Its robust performance guarantees consistent and reproducible results, empowering researchers to confidently analyze BARD1 protein expression across multiple experiments.

Furthermore, the BARD1 Polyclonal Antibody is manufactured under stringent quality control measures, adhering to the highest industry standards. Each batch undergoes rigorous testing to ensure batch-to-batch consistency, guaranteeing optimal performance and reliability. This commitment to quality ensures that researchers can rely on the BARD1 Polyclonal Antibody for consistent and accurate results, enhancing the efficiency and effectiveness of their scientific endeavors.

In summary, the BARD1 Polyclonal Antibody is a state-of-the-art scientific tool that offers exceptional specificity, sensitivity, and reliability for the detection of BARD1 protein expression. Its versatility and robust performance make it an invaluable asset for researchers in various fields, enabling comprehensive investigations into the role of BARD1 in cellular processes and disease mechanisms. Trust in the BARD1 Polyclonal Antibody to elevate your research to new heights of precision and accuracy.