BCAR3 Polyclonal Antibody

Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. BCAR3 (breast cancer anti-estrogen resistance 3) encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for BCAR3.

The BCAR3 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of BCAR3 protein expression in various biological samples. This antibody has been meticulously developed using advanced immunization techniques, ensuring its exceptional sensitivity and specificity.

The BCAR3 Polyclonal Antibody exhibits a strong affinity towards BCAR3, a crucial protein involved in cell adhesion and migration processes. By targeting BCAR3, this antibody enables researchers to gain valuable insights into the molecular mechanisms underlying these fundamental cellular functions.

This antibody has been extensively validated through rigorous testing procedures, guaranteeing its superior performance and accuracy. It exhibits minimal cross-reactivity with other proteins, ensuring precise and reliable results. Furthermore, the BCAR3 Polyclonal Antibody demonstrates excellent reproducibility, making it an ideal choice for both routine laboratory experiments and more demanding research applications.

The BCAR3 Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is available in various sizes to accommodate different experimental needs. Each batch of this antibody undergoes strict quality control measures to ensure consistent and reliable performance.

In summary, the BCAR3 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of BCAR3 protein expression. Its exceptional sensitivity, specificity, and reproducibility make it an invaluable asset for researchers studying cell adhesion and migration processes.