Bcl-10 Polyclonal Antibody

BCL10 (B-cell CLL/lymphoma 10) was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by BCL10 contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants.

Introducing the Bcl-10 Polyclonal Antibody, a cutting-edge scientific tool designed to revolutionize your research in the field of immunology. This meticulously crafted antibody is specifically engineered to target and detect Bcl-10, a crucial protein involved in various cellular processes, including apoptosis and immune response regulation.

With its exceptional specificity and sensitivity, the Bcl-10 Polyclonal Antibody offers unparalleled accuracy in identifying and quantifying Bcl-10 expression levels in a wide range of biological samples. Its polyclonal nature ensures enhanced binding affinity, enabling reliable detection even in low abundance scenarios.

Crafted using state-of-the-art techniques, this antibody exhibits exceptional reproducibility, guaranteeing consistent and reliable results across multiple experiments. Its high affinity for Bcl-10 ensures minimal cross-reactivity, minimizing the risk of false positives and false negatives, thus providing you with precise and trustworthy data.

The Bcl-10 Polyclonal Antibody is compatible with various immunological techniques, including Western blotting, immunohistochemistry, and immunofluorescence, allowing for versatile applications in diverse experimental setups. Its robust performance across different sample types, such as cell lysates, tissue sections, and whole blood, further enhances its versatility and utility.

Furthermore, this antibody is manufactured under stringent quality control measures, ensuring batch-to-batch consistency and reliability. Each vial is meticulously tested to meet the highest standards of purity, specificity, and functionality, guaranteeing optimal performance and reproducibility.

In summary, the Bcl-10 Polyclonal Antibody represents a breakthrough in immunological research, offering exceptional specificity, sensitivity, and versatility. With its reliable performance and precise detection capabilities, this antibody is an indispensable tool for scientists and researchers aiming to unravel the intricate mechanisms underlying cellular processes involving Bcl-10.