Bcl-x Polyclonal Antibody

The protein (BCL2 like 1) encoded by BCL2L1belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.

The Bcl-x Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Bcl-x protein expression in various biological samples. This antibody is produced through a rigorous process, ensuring high quality and reliability in experimental results.

The Bcl-x Polyclonal Antibody exhibits exceptional affinity and specificity towards Bcl-x, a member of the Bcl-2 protein family known for its crucial role in regulating apoptosis. With its ability to bind to Bcl-x with high affinity, this antibody enables accurate and precise quantification of Bcl-x protein levels in cells and tissues.

This antibody is suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated in various experimental settings, demonstrating consistent and reproducible results. Its versatility allows researchers to explore the expression and localization of Bcl-x in different cell types and tissues.

The Bcl-x Polyclonal Antibody is manufactured using state-of-the-art techniques and undergoes stringent quality control measures to ensure batch-to-batch consistency. It is supplied as a ready-to-use solution, eliminating the need for time-consuming antibody preparation. Its long shelf life and stability make it an ideal choice for long-term storage and repeated experiments.

In summary, the Bcl-x Polyclonal Antibody is a reliable and efficient tool for studying Bcl-x protein expression. Its high specificity, sensitivity, and versatility make it an invaluable asset for researchers in the field of apoptosis and cell death.