BCoR Polyclonal Antibody

The protein (BCL6 corepressor) encoded by BCOR was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for BCOR. A pseudogene of this gene is found on chromosome Y.

The BCoR Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of the human BCoR protein. The resulting polyclonal antibody has been extensively validated for its specificity and sensitivity in detecting endogenous BCoR protein in various cell types and tissues.

The BCoR Polyclonal Antibody is suitable for use in a variety of applications, including Western blotting, immunoprecipitation, and immunofluorescence. It has been shown to detect BCoR protein in human, mouse, and rat samples, making it a versatile tool for researchers working with different model organisms.

This antibody is supplied as a purified IgG fraction, which has been affinity-purified using a BCoR peptide column. It is provided in a liquid format, ready for use in various applications. The BCoR Polyclonal Antibody is available in different sizes to suit the needs of different research projects.

Overall, the BCoR Polyclonal Antibody is a reliable and high-quality tool for researchers studying the BCoR protein and its functions in various biological processes. Its specificity, sensitivity, and versatility make it an ideal choice for a wide range of research applications.