BCSC-1 Polyclonal Antibody

VWA5A (von Willebrand factor A domain containing 5A), also known as BCSC-1 (breast cancer suppressor candidate 1) or LOH11CR2A (loss of heterozygosity 11 chromosomal region 2 gene A protein), is a 786 amino acid protein containing one VIT domain and one VWFA domain. VWA5A is expressed at low levels in various tissues, with no expression found in 80% of tumor cell lines. Likely acting as a tumor suppressor gene, deletion of VWA5A leads to loss of heterozygosity (LOH) in breast and ovarian tumors, and may have an important role as a potential gene therapy target. Abnormal expression of VWA5A may lead to an increase in adhesion of CNE-2L2 cells associated with an increase in expression of E-cadherin, alpha-catenin, and p53, resulting in a decrease of malignant activity in cells with ectopic expression of VWA5A. Existing as four alternatively spliced isoforms, the gene encoding VWA5A maps to human chromosome 11q24.2.

Introducing the BCSC-1 Polyclonal Antibody, a cutting-edge scientific tool meticulously designed to revolutionize research in the field of biomedicine. This high-quality antibody is specifically engineered to target and detect BCSC-1, a crucial protein involved in various cellular processes.

Crafted with utmost precision and expertise, the BCSC-1 Polyclonal Antibody exhibits exceptional specificity and sensitivity, ensuring accurate and reliable results. Its unique formulation guarantees minimal cross-reactivity, enabling researchers to confidently explore the intricate mechanisms associated with BCSC-1.

The BCSC-1 Polyclonal Antibody boasts an impressive range of applications, making it an indispensable asset in numerous experimental settings. From immunohistochemistry and immunofluorescence to western blotting and flow cytometry, this versatile antibody seamlessly adapts to diverse methodologies, facilitating comprehensive investigations into BCSC-1's role in disease progression and therapeutic interventions.

With its superior performance and exceptional reproducibility, the BCSC-1 Polyclonal Antibody empowers scientists to delve deeper into the intricate complexities of BCSC-1 biology. Its robust and reliable results pave the way for groundbreaking discoveries and advancements in the field of biomedicine.

Invest in the BCSC-1 Polyclonal Antibody today and unlock the potential for groundbreaking research. Experience the unparalleled precision and reliability that this state-of-the-art antibody offers, propelling your scientific endeavors to new heights.