Biotin Anti-Human CD58 Antibody[TS2/9.1]

Biotin Anti-Human CD58 Antibody[TS2/9.1]

The Biotin Anti-Human CD58 Antibody[TS2/9.1] is a highly specific monoclonal antibody that targets the CD58 antigen, also known as Lymphocyte Function-Associated Antigen 3 (LFA-3). This antibody is conjugated with biotin, a small molecule that can be easily detected using streptavidin-based detection systems. The TS2/9.1 clone of this antibody has been extensively characterized and validated for use in various applications, including flow cytometry, immunohistochemistry, and western blotting.

CD58 is a cell surface glycoprotein that is expressed on various cell types, including T cells, B cells, natural killer cells, and monocytes. It plays a critical role in immune cell activation and adhesion by binding to its receptor, CD2, on neighboring cells. Dysregulation of CD58 expression has been implicated in various diseases, including autoimmune disorders, infectious diseases, and cancer. Therefore, the Biotin Anti-Human CD58 Antibody[TS2/9.1] can be a valuable tool for studying the role of CD58 in these diseases and for developing novel therapeutic strategies.

The Biotin Anti-Human CD58 Antibody[TS2/9.1] is supplied as a purified antibody in phosphate-buffered saline (PBS) with 0.1% sodium azide as a preservative. It is recommended to store the antibody at 4°C and avoid repeated freeze-thaw cycles. The antibody can be used at a concentration of 1-10 µg/mL for flow cytometry and immunohistochemistry, and at a concentration of 0.1-1 µg/mL for western blotting. The antibody has been validated for use in human samples, but cross-reactivity with other species has not been tested. Overall, the Biotin Anti-Human CD58 Antibody[TS2/9.1] is a reliable and specific tool for studying CD58 expression and function in various applications.