BMP7; OP1; Bone morphogenetic protein 7; BMP-7; Osteogenic protein 1; OP-1; Eptotermin alfa
Applications:
WB;IHC;IF;ELISA
Recommended Dilutions:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen:
The antiserum was produced against synthesized peptide derived from human BMP-7. AA range:124-173
Storage:
Rabbit
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
55kD
GeneID（Human）:
655
Human Swiss-Prot No:
P18075
Cellular localization:
Secreted.
Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients. [provided by RefSeq, Jul 2016],
Western Blot analysis of various cells using BMP-7 Polyclonal Antibody diluted at 1:500
Western Blot analysis of rat-musle cells using BMP-7 Polyclonal Antibody diluted at 1:500
Immunohistochemistry analysis of BMP-7 antibody in paraffin-embedded human tonsil tissue.
Western blot analysis of lysate from Jurkat cells, using BMP-7 antibody.