Growth/differentiation factor 2 (GDF-2;Bone morphogenetic protein 9;BMP-9)
Applications:
IHC;IF;ELISA
Recommended Dilutions:
IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen:
Synthetic peptide from human protein at AA range: 371-420
Storage:
Rabbit
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
GeneID（Human）:
2658
Human Swiss-Prot No:
Q9UK05
Cellular localization:
Secreted .
Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia. [provided by RefSeq, Jul 2016],
Immunohistochemical analysis of paraffin-embedded human-liver-cancer, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-liver-cancer, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200