BNIP-2 Polyclonal Antibody

BNIP2 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein (BCL2 interacting protein 2) also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. Alternate splicing results in multiple transcript variants.

The BNIP-2 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of BNIP-2 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human BNIP-2 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the target protein, making it an ideal tool for various applications in research and diagnostics.

The BNIP-2 Polyclonal Antibody is suitable for use in Western blotting, immunohistochemistry, and immunofluorescence assays. It has been validated for use in human, mouse, and rat samples, and has been shown to detect endogenous BNIP-2 protein in various tissues and cell lines. This antibody is supplied as a purified IgG fraction, and has been tested for its purity, specificity, and activity.

The BNIP-2 Polyclonal Antibody is a valuable tool for researchers studying the role of BNIP-2 protein in various cellular processes, including apoptosis, autophagy, and mitochondrial function. It can also be used in clinical settings for the diagnosis and monitoring of diseases associated with BNIP-2 dysregulation, such as cancer and neurodegenerative disorders.

Overall, the BNIP-2 Polyclonal Antibody is a reliable and high-quality reagent that offers excellent performance and versatility for a wide range of applications in research and diagnostics. Its specificity, sensitivity, and reproducibility make it an essential tool for any laboratory studying BNIP-2 protein and its functions.