BNIP-3 Polyclonal Antibody

BNIP3 (BCL2 interacting protein 3) is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. BNIP3 is silenced in tumors by DNA methylation.

The BNIP-3 Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of BNIP-3 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human BNIP-3 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards BNIP-3 protein, making it an ideal reagent for various applications such as Western blotting, immunohistochemistry, and immunofluorescence.

The BNIP-3 Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using a column containing immobilized BNIP-3 protein. This ensures that the antibody is highly specific and free from any non-specific binding. The antibody is also validated for its specificity and sensitivity using various techniques such as ELISA, Western blotting, and immunohistochemistry.

The BNIP-3 Polyclonal Antibody is suitable for use in various research areas such as cancer biology, apoptosis, autophagy, and mitochondrial function. It is also compatible with various sample types such as cell lysates, tissue homogenates, and serum. The antibody is provided in a convenient format, with different sizes available to suit different experimental needs.

In summary, the BNIP-3 Polyclonal Antibody is a reliable and high-quality reagent that offers excellent performance in the detection and quantification of BNIP-3 protein. Its high specificity and sensitivity make it an ideal tool for various research applications, and its convenient format ensures ease of use and flexibility.