Brg-1 Polyclonal Antibody

The protein encoded by SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4) is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in SMARCA4 cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for SMARCA4.

The Brg-1 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Brg-1 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity.

The Brg-1 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It enables researchers to investigate the role of Brg-1 in cellular processes, such as gene regulation, chromatin remodeling, and DNA repair.

With its superior specificity, this antibody allows for accurate and precise identification of Brg-1 protein in complex biological systems. Its robust performance ensures reliable and reproducible results, making it an indispensable tool for both basic research and clinical studies.

The Brg-1 Polyclonal Antibody is manufactured under strict quality control standards, guaranteeing consistent and reliable performance batch after batch. It is supplied in a convenient format, ready to use for various experimental setups.

Choose the Brg-1 Polyclonal Antibody for its exceptional specificity, sensitivity, and reliability, and unlock new insights into the intricate mechanisms of Brg-1 protein function.