BTBD6 Polyclonal Antibody

BTBD6 (BTB/POZ domain-containing protein 6), also known as BDPL or lens BTB domain protein, is a 410 amino acid protein that contains one BTB/POZ domain and is specifically expressed in the lens. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD6 may play a role in transcription regulation in the lens.

The BTBD6 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of BTBD6 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity. With its exceptional performance, the BTBD6 Polyclonal Antibody offers researchers a valuable tool for investigating the role of BTBD6 in cellular processes and disease mechanisms.

The BTBD6 Polyclonal Antibody exhibits excellent specificity, as it has been extensively validated against a wide range of targets to ensure minimal cross-reactivity. This antibody recognizes endogenous levels of BTBD6 protein, making it suitable for various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The BTBD6 Polyclonal Antibody is manufactured under strict quality control standards, guaranteeing batch-to-batch consistency and reproducibility. It is supplied as a liquid formulation, ready for immediate use, eliminating the need for time-consuming reconstitution steps. The antibody is provided in a convenient size, allowing for multiple experiments and minimizing waste.

In summary, the BTBD6 Polyclonal Antibody is a reliable and specific tool for the detection and analysis of BTBD6 protein expression. Its exceptional performance, high specificity, and ease of use make it an ideal choice for researchers studying the function and regulation of BTBD6 in various biological contexts.