Bub1 Polyclonal Antibody

BUB1 (BUB1 mitotic checkpoint serine/threonine kinase) encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in BUB1 have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.

The BUB1 Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity. The BUB1 Polyclonal Antibody is ideal for use in immunohistochemistry, western blotting, and other applications where high sensitivity and specificity are required.

This antibody is designed to target the BUB1 protein, which is a key regulator of the mitotic checkpoint. The mitotic checkpoint is a critical mechanism that ensures proper chromosome segregation during cell division. Dysregulation of this checkpoint can lead to chromosomal instability and contribute to the development of cancer.

The BUB1 Polyclonal Antibody is produced using state-of-the-art techniques and is rigorously tested to ensure its quality and performance. This antibody is supplied in a convenient format and is ready to use in a variety of applications.

In summary, the BUB1 Polyclonal Antibody is a highly specific and sensitive antibody that is ideal for use in various research applications. Its ability to target the BUB1 protein makes it an essential tool for studying the mitotic checkpoint and its role in cancer development. With its high quality and performance, the BUB1 Polyclonal Antibody is a valuable addition to any research laboratory.