c-Kit(Phospho-Tyr719) Rabbit Polyclonal Antibody

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor| also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors| mast cell disease| acute myelogenous lukemia| and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

The c-Kit(Phospho-Tyr719) Rabbit Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of c-Kit protein phosphorylated at tyrosine 719. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring excellent performance and reliability in various applications, including Western blotting, immunoprecipitation, and immunohistochemistry.

The c-Kit protein, also known as CD117 or stem cell factor receptor, plays a crucial role in various cellular processes, including cell proliferation, differentiation, and survival. Phosphorylation of tyrosine 719 is a key event in the activation of c-Kit signaling pathway, which is involved in the regulation of hematopoiesis, melanogenesis, and gametogenesis.

This antibody has been rigorously validated and characterized to ensure its specificity and sensitivity. It exhibits minimal cross-reactivity with other proteins, ensuring accurate and reliable results. The high affinity and specificity of this antibody make it an ideal tool for studying the activation and regulation of c-Kit signaling pathway in various biological systems.

The c-Kit(Phospho-Tyr719) Rabbit Polyclonal Antibody is supplied as a liquid formulation, ready to use for various applications. It is provided in a convenient size and format, allowing for easy handling and storage. The antibody is stable and long-lasting, ensuring consistent and reproducible results over time.

In summary, the c-Kit(Phospho-Tyr719) Rabbit Polyclonal Antibody is a valuable tool for researchers studying the role of c-Kit signaling pathway in various biological processes. Its high specificity, sensitivity, and reliability make it an essential component of any research project aiming to understand the molecular mechanisms underlying cellular processes regulated by c-Kit protein.