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ELK Biotechnology

ES5632

C3G (phospho Tyr504) Rabbit Polyclonal Antibody

C3G (phospho Tyr504) Rabbit Polyclonal Antibody

Size

C3G (phospho Tyr504) Rabbit Polyclonal Antibody

Overview

Product name: C3G (phospho Tyr504) rabbit pAb
Alternative Names: RAPGEF1; GRF2; Rap guanine nucleotide exchange factor 1; CRK SH3-binding GNRP; Guanine nucleotide-releasing factor 2; Protein C3G
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human RapGEF1 around the phosphorylation site of Tyr504. AA range:470-519
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 120kD
GeneID（Human）: 2889
Human Swiss-Prot No: Q13905
Cellular localization: Early endosome .
Background: This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Rat;Mouse;
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