CA III Polyclonal Antibody

Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal.

The CA III Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of Carbonic Anhydrase III (CA III) protein in various biological samples. This antibody is produced by immunizing rabbits with a purified recombinant CA III protein, ensuring its high affinity and specificity towards the target protein.

Carbonic Anhydrase III is an enzyme that plays a crucial role in the regulation of acid-base balance and pH homeostasis in various tissues, including skeletal muscle and liver. It is also involved in the detoxification of reactive oxygen species and the protection against oxidative stress. The CA III Polyclonal Antibody enables researchers to investigate the expression and localization of CA III in different tissues and cell types, providing valuable insights into its physiological and pathological functions.

The CA III Polyclonal Antibody exhibits exceptional sensitivity and specificity, allowing for accurate and reliable detection of CA III protein even at low concentrations. It has been extensively validated in various experimental techniques, including Western blotting, immunohistochemistry, and immunofluorescence. This antibody demonstrates minimal cross-reactivity with other carbonic anhydrase isoforms, ensuring the specificity of the detected signal.

With its superior performance and versatility, the CA III Polyclonal Antibody is an indispensable tool for researchers studying the role of CA III in various biological processes and diseases. Its high-quality formulation guarantees consistent and reproducible results, making it an ideal choice for both basic research and clinical applications.