CA VA Polyclonal Antibody

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis. CA5A gene maps to chromosome 16q24.3 and an unprocessed pseudogene has been assigned to 16p12-p11.2.

The CA VA Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of CA VA protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of the CA VA protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the target protein, making it an ideal tool for various research applications.

The CA VA Polyclonal Antibody is suitable for use in a variety of immunoassays, including Western blotting, ELISA, immunohistochemistry, and immunofluorescence. It has been validated for use in human, mouse, and rat samples, and has been shown to exhibit minimal cross-reactivity with other proteins. The antibody is supplied as a purified IgG fraction, and has been tested for its ability to detect endogenous levels of CA VA protein in various tissues and cell lines.

In summary, the CA VA Polyclonal Antibody is a reliable and versatile tool for the detection and quantification of CA VA protein in various biological samples. Its high specificity and sensitivity make it an ideal choice for researchers studying the role of CA VA in various physiological and pathological processes.