CA XII Polyclonal Antibody

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. The gene product CA12 (carbonic anhydrase 12) is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for CA12.

The Cadherin-7 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Cadherin-7 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity towards Cadherin-7.

Cadherin-7, also known as CDH7, is a calcium-dependent cell adhesion molecule that plays a crucial role in cell-cell adhesion and tissue morphogenesis. It is primarily expressed in neural tissues, including the brain and spinal cord, as well as in certain epithelial tissues. Dysregulation of Cadherin-7 expression has been implicated in various pathological conditions, such as cancer metastasis and neurodevelopmental disorders.

The Cadherin-7 Polyclonal Antibody has been extensively validated for its specificity and performance in various experimental applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other cadherin family members, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without compromising its quality. The Cadherin-7 Polyclonal Antibody is manufactured under strict quality control standards, ensuring batch-to-batch consistency and reproducibility.

In summary, the Cadherin-7 Polyclonal Antibody is a valuable tool for researchers studying Cadherin-7 protein expression and its functional implications. Its high specificity, sensitivity, and versatility make it an ideal choice for a wide range of applications in both basic and clinical research.