CA XIII Polyclonal Antibody

Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide. CAs show extensive diversity in their distribution and subcellular localization. They are involved in a variety of biological processes, including calcification, bone resorption, respiration, acid-base balance and the formation of aqueous humor, saliva, gastric juice and cerebrospinal fluid. CA XIII, also referred to as carbonate dehydratase XIII, is predominantly expressed in spleen, prostate, thymus, ovary, testis, colon and small intestine localizing to the cytoplasm. It exhibits highest homology with family members CA I, CA II and CA III. CA XIII may play a role in embryogenesis. Efficient inhibitors of CA XIII activity are sulfanilyl-sulfonamide type inhibitors.

The CA XIII Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of carbonic anhydrase XIII (CA XIII) protein in various biological samples. This antibody is produced using state-of-the-art techniques, ensuring exceptional quality and performance.

Carbonic anhydrase XIII is an enzyme that plays a crucial role in the regulation of acid-base balance and pH homeostasis in the body. It is predominantly expressed in the kidney, where it is involved in the reabsorption of bicarbonate ions. Abnormal expression or activity of CA XIII has been implicated in various pathological conditions, making it an important target for research and diagnostic purposes.

The CA XIII Polyclonal Antibody exhibits high affinity and specificity towards CA XIII protein, enabling accurate and sensitive detection. It has been extensively validated in a range of experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence. This antibody demonstrates minimal cross-reactivity with other carbonic anhydrase isoforms, ensuring reliable and specific results.

With its superior performance and versatility, the CA XIII Polyclonal Antibody is an indispensable tool for researchers and clinicians working in the fields of molecular biology, biochemistry, and medicine. Its application extends to various research areas, including renal physiology, acid-base regulation, and the development of therapeutic strategies targeting CA XIII.

Order the CA XIII Polyclonal Antibody today and unlock the potential for groundbreaking discoveries and advancements in the understanding of carbonic anhydrase XIII function and its implications in human health and disease.