CAD(phospho-Ser1859) Rabbit Polyclonal Antibody

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II)| aspartate transcarbamoylase| and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade| which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.

The CAD(phospho-Ser1859) Rabbit Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of CAD protein phosphorylated at Ser1859. This antibody has been rigorously validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The CAD protein plays a crucial role in the de novo pyrimidine biosynthesis pathway, and its phosphorylation at Ser1859 has been implicated in the regulation of CAD activity. This antibody specifically recognizes the phosphorylated form of CAD, allowing for the investigation of its functional significance in cellular processes.

The CAD(phospho-Ser1859) Rabbit Polyclonal Antibody exhibits exceptional sensitivity and specificity, ensuring reliable and accurate results. It has been extensively tested and validated using a variety of cell lines and tissues, demonstrating its robust performance across different experimental conditions.

With its high affinity and selectivity, this antibody offers researchers a valuable tool for studying CAD phosphorylation and its implications in cellular physiology and disease. Its versatility in various applications makes it suitable for a wide range of research areas, including cancer biology, cell signaling, and drug discovery.

The CAD(phospho-Ser1859) Rabbit Polyclonal Antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and consistent results. It is produced using state-of-the-art techniques, guaranteeing batch-to-batch consistency and reproducibility.

In summary, the CAD(phospho-Ser1859) Rabbit Polyclonal Antibody is a reliable and efficient tool for investigating the phosphorylation status of CAD protein at Ser1859. Its exceptional sensitivity, specificity, and versatility make it an invaluable asset for researchers in various fields of study.