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ELK Biotechnology
SKU(재고 관리 코드):ES10503
CAD12 Rabbit Polyclonal Antibody
CAD12 Rabbit Polyclonal Antibody
CAD12 Rabbit Polyclonal Antibody
Overview
| Product name: | CAD12 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 500-580 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 87kD |
| GeneID（Human）: | 1010 |
| Human Swiss-Prot No: | P55289 |
| Cellular localization: | Cell membrane; Single-pass type I membrane protein. |
| Background: | This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. [p |
| Species Reactivity: | Human;Mouse |
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