Cadherin-16 Polyclonal Antibody

CDH16 is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

The Cadherin-19 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Cadherin-19 protein expression in various biological samples. This antibody is produced through a rigorous process, ensuring its high affinity and sensitivity towards Cadherin-19.

Cadherin-19 is a calcium-dependent cell adhesion molecule that plays a crucial role in the maintenance of tissue integrity and cell-cell adhesion. It is primarily expressed in the kidney, lung, and gastrointestinal tract, where it contributes to the structural integrity and function of these organs. Dysregulation of Cadherin-19 expression has been implicated in various pathological conditions, including renal diseases, lung disorders, and gastrointestinal disorders.

The Cadherin-19 Polyclonal Antibody has been extensively validated for its specificity and performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other cadherin family members, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without compromising its quality. The Cadherin-19 Polyclonal Antibody is manufactured under strict quality control standards, ensuring batch-to-batch consistency and reproducibility.

Researchers and scientists can confidently rely on the Cadherin-19 Polyclonal Antibody to investigate the role of Cadherin-19 in various physiological and pathological processes. Its exceptional specificity, sensitivity, and reliability make it an indispensable tool for studying Cadherin-19 expression and function in diverse research areas, including developmental biology, tissue engineering, and disease mechanisms.

Choose the Cadherin-19 Polyclonal Antibody for accurate and reproducible results, enabling groundbreaking discoveries in the field of Cadherin-19 research.