Cadherin-20 Polyclonal Antibody

CDH20 is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The cadherin 20 is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.

The Cadherin-20 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Cadherin-20 protein expression in various biological samples. This antibody is produced through a rigorous process, ensuring its high affinity and sensitivity towards Cadherin-20.

Cadherin-20, also known as CDH20, is a calcium-dependent cell adhesion molecule that plays a crucial role in cell-cell adhesion and tissue morphogenesis. It is predominantly expressed in the brain, specifically in the hippocampus and cerebellum, where it contributes to neuronal development and synaptic plasticity.

The Cadherin-20 Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes endogenous levels of Cadherin-20 protein, enabling accurate and reliable quantification of its expression in different tissues and cell types.

This antibody is produced using high-quality materials and advanced techniques, ensuring batch-to-batch consistency and reproducibility. It has been extensively validated for its specificity, sensitivity, and minimal cross-reactivity with other related proteins. The Cadherin-20 Polyclonal Antibody guarantees reliable and reproducible results, making it an indispensable tool for researchers studying Cadherin-20 function and its implications in various biological processes.

With its superior performance and exceptional quality, the Cadherin-20 Polyclonal Antibody is an invaluable asset for scientists and researchers in the fields of neuroscience, developmental biology, and cell biology. It provides a reliable means to investigate the role of Cadherin-20 in cellular adhesion, neuronal development, and synaptic plasticity, ultimately contributing to a better understanding of complex biological processes.