Cadherin-9 Polyclonal Antibody

CDH9 encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins.

The Cadherin-9 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Cadherin-9 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Cadherin-9 protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid solution in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The Cadherin-9 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to specifically recognize Cadherin-9 protein in human, mouse, and rat tissues, making it a versatile tool for researchers studying Cadherin-9 expression and function in different species.

This antibody is suitable for use in both basic research and clinical applications, including cancer research, developmental biology, and neuroscience. Its high specificity and sensitivity make it an ideal tool for studying the role of Cadherin-9 in various biological processes and diseases.

In summary, the Cadherin-9 Polyclonal Antibody is a reliable and effective tool for the detection of Cadherin-9 protein in various biological samples. Its high specificity and sensitivity make it a valuable asset for researchers studying Cadherin-9 expression and function in different species and applications.