CAF-1 p150 Polyclonal Antibody

Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B; MIM 601245), and p150 (CHAF1A) subunits that assembles histone octamers onto replicating DNA in vitro.

The CAF-1 p150 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of CAF-1 p150 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human CAF-1 p150 protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The CAF-1 p150 Polyclonal Antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to specifically recognize CAF-1 p150 protein in human, mouse, and rat tissues and cell lines. The antibody has a high affinity and sensitivity, allowing for the detection of low levels of CAF-1 p150 protein in samples.

This antibody is an essential tool for researchers studying DNA replication and repair, chromatin assembly, and epigenetic regulation. It can be used to investigate the role of CAF-1 p150 protein in these processes and to identify potential therapeutic targets for diseases associated with DNA damage and chromatin dysfunction.

In summary, the CAF-1 p150 Polyclonal Antibody is a reliable and effective tool for the detection of CAF-1 p150 protein in various biological samples. Its high specificity and sensitivity make it an ideal choice for researchers studying DNA replication and repair, chromatin assembly, and epigenetic regulation.