Caldesmon Polyclonal Antibody

CALD1 (caldesmon 1) encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

The Caldesmon Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of caldesmon protein in various biological samples. This antibody is produced through a rigorous process of immunization using purified caldesmon protein, ensuring its exceptional specificity and sensitivity.

The Caldesmon Polyclonal Antibody exhibits excellent performance in a wide range of applications, including western blotting, immunohistochemistry, and immunofluorescence. It enables researchers to accurately visualize and quantify caldesmon protein expression in tissues and cells, facilitating the investigation of its role in various physiological and pathological processes.

This antibody is meticulously validated to ensure consistent and reproducible results. It demonstrates minimal cross-reactivity with other proteins, guaranteeing the specificity of the detected signal. Furthermore, it exhibits high affinity and sensitivity, allowing for the detection of even low-abundance caldesmon protein.

The Caldesmon Polyclonal Antibody is supplied in a convenient and ready-to-use format, eliminating the need for time-consuming preparation. It is provided in a liquid formulation, ensuring ease of use and minimizing the risk of experimental errors. The antibody is also available in different sizes to accommodate various experimental requirements.

With its exceptional specificity, sensitivity, and reliability, the Caldesmon Polyclonal Antibody is an indispensable tool for researchers studying caldesmon protein and its involvement in cellular processes. It offers a valuable means to advance scientific understanding and contribute to the development of novel therapeutic strategies.