CaMKV Polyclonal Antibody

The Ca2+/calmodulin-dependent protein kinases (CaMKs) comprise a structurally related subfamily of serine/threonine kinases. CAMKV (CaM kinase-like vesicle-associated), also known as 1G5 or VACAMKL, is a 501 amino acid protein that localizes to cytoplasmic vesicles, as well as to the cell membrane, and contains one protein kinase domain. Although a member of the CaMK family, CaMKV is thought to be catalytically inactive, but it may play a role in vesicle function and nervous system development. Multiple isoforms of CaMKV exist due to alternative splicing events. The gene encoding CaMKV maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

The CaMKV Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of CaMKV protein expression in various biological samples. This antibody is produced through a rigorous process, ensuring its high affinity and specificity towards CaMKV.

CaMKV, also known as Calcium/calmodulin-dependent protein kinase V, is a crucial regulator of intracellular calcium signaling pathways. It plays a significant role in various cellular processes, including neuronal development, synaptic plasticity, and learning and memory. The CaMKV Polyclonal Antibody enables researchers to investigate the involvement of CaMKV in these processes and explore its potential as a therapeutic target.

This antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been validated for use in multiple species, ensuring its versatility and applicability across various experimental models.

The CaMKV Polyclonal Antibody offers several advantages over other available antibodies. Its high sensitivity allows for the detection of low levels of CaMKV protein, enabling researchers to obtain accurate and reliable results. Additionally, its polyclonal nature enhances the signal intensity, providing enhanced visualization and quantification of CaMKV expression.

Furthermore, this antibody is manufactured using state-of-the-art techniques and undergoes stringent quality control measures to ensure batch-to-batch consistency and reproducibility. It is supplied in a convenient and ready-to-use format, eliminating the need for time-consuming and complex preparation steps.

In summary, the CaMKV Polyclonal Antibody is a valuable tool for researchers studying CaMKV protein expression and its role in cellular processes. Its high specificity, sensitivity, and versatility make it an ideal choice for a wide range of applications. With its exceptional performance and reliable results, this antibody is an indispensable asset for advancing scientific knowledge in the field of calcium signaling and related research areas.