Casein Kinase I Alpha Polyclonal Antibody

Casein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. Casein kinase I family members, which include casein kinase Iα, Iγ, Iδ and Iε, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair, membrane trafficking, circadian rhythm, cell cycle progression, chromosome segregation, apoptosis and cellular differentiation.

Casein kinase I isoform alpha-like (CSNK1A1L) is a 337 amino acid protein that shares a high degree of sequence similarity with the alpha isoform of casein kinase 1. CSNK1A1L resides in the cytoplasm and participates in the Wnt signaling pathway. By utilizing ATP within its protein kinase domain, CSNK1A1L phosphorylates a large number of proteins.

The Casein Kinase I Alpha Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Casein Kinase I Alpha protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the N-terminal region of human Casein Kinase I Alpha protein.

The antibody has been purified using protein A affinity chromatography and is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. The Casein Kinase I Alpha Polyclonal Antibody is a valuable tool for researchers studying the role of Casein Kinase I Alpha in various cellular processes, including cell cycle regulation, DNA repair, and circadian rhythm.

With its high specificity and sensitivity, this antibody is an essential reagent for any laboratory investigating the function of Casein Kinase I Alpha protein.