Caspase 2 Rabbit Polyclonal Antibody

alternative products:Isoforms differ in the N- and C-termini|Catalytic activity:Strict requirement for an Asp residue at P1| with 316-asp being essential for proteolytic activity and has a preferred cleavage sequence of Val-Asp-Val-Ala-Asp-|-.|Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.|PTM:The mature protease can process its own propeptide| but not that of other caspases.|Belongs to the peptidase C14A family.|Contains 1 CARD domain.|subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers| each one formed by a p18 subunit and a p12 subunit. Interacts with LRDD.|tissue specificity:Expressed at higher levels in the embryonic lung| liver and kidney than in the heart and brain. In adults| higher level expression is seen in the placenta| lung| kidney| and pancreas than in the heart| brain| liver and skeletal muscle.|

The Caspase 2 Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of caspase 2 protein in various biological samples. This antibody has been rigorously tested and validated to ensure its reliability and accuracy in research applications.

Caspase 2 is a crucial enzyme involved in the initiation and execution of apoptosis, a programmed cell death process essential for maintaining tissue homeostasis and eliminating damaged or unwanted cells. Dysregulation of caspase 2 has been implicated in various diseases, including cancer, neurodegenerative disorders, and autoimmune conditions.

The Caspase 2 Rabbit Polyclonal Antibody exhibits exceptional affinity and selectivity towards caspase 2, enabling precise detection and measurement of its expression levels. This antibody has been produced using high-quality rabbit polyclonal antibodies, ensuring superior sensitivity and specificity.

This antibody is suitable for a wide range of applications, including Western blotting, immunohistochemistry, immunofluorescence, and flow cytometry. It has been optimized for use in both human and animal samples, making it a versatile tool for researchers in various fields.

The Caspase 2 Rabbit Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a vial with an appropriate concentration, ensuring optimal performance and minimizing wastage.

In summary, the Caspase 2 Rabbit Polyclonal Antibody is a reliable and efficient tool for the detection and quantification of caspase 2 protein. Its high specificity, sensitivity, and versatility make it an invaluable asset for researchers studying apoptosis and its implications in various diseases.