Caspase-9 Polyclonal Antibody

CASP9 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.

The Cathepsin D Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Cathepsin D protein in various biological samples. This antibody is produced using advanced techniques, ensuring high affinity and specificity towards Cathepsin D.

Cathepsin D is a lysosomal protease that plays a crucial role in the degradation of intracellular proteins. It is involved in various physiological and pathological processes, including cell proliferation, apoptosis, and tumor progression. The Cathepsin D Polyclonal Antibody enables researchers to investigate the expression and localization of Cathepsin D in different tissues and cell types.

This antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other related proteins, ensuring accurate and reliable results.

The Cathepsin D Polyclonal Antibody is supplied as a liquid formulation, ready to use for immediate experimentation. It is provided in a convenient size, allowing for multiple experiments without the need for frequent reordering.

With its exceptional sensitivity and specificity, the Cathepsin D Polyclonal Antibody is an indispensable tool for researchers studying the role of Cathepsin D in various biological processes. Its reliable performance and ease of use make it an ideal choice for both basic research and clinical applications.