Caspase12 Polyclonal Antibody

Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. CASP12 is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of CASP12 mediates apoptosis in response to endoplasmic reticulum stress. However, in humans CASP12 contains a polymorphism for the presence or absence of a premature stop codon.

The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for CASP12.

The Caspase12 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Caspase12 protein in various biological samples. This antibody is produced using high-quality polyclonal antibodies that have been purified and validated for their specificity and sensitivity. The Caspase12 Polyclonal Antibody is an essential tool for researchers studying the role of Caspase12 in various cellular processes, including apoptosis and inflammation.

This antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. The Caspase12 Polyclonal Antibody is a reliable and effective tool for researchers seeking to investigate the function of Caspase12 in various biological systems.

The Caspase12 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Caspase12 protein in various biological samples. This antibody is produced using high-quality polyclonal antibodies that have been purified and validated for their specificity and sensitivity.

The Caspase12 Polyclonal Antibody is an essential tool for researchers studying the role of Caspase12 in various cellular processes, including apoptosis and inflammation. This antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. The Caspase12 Polyclonal Antibody is a reliable and effective tool for researchers seeking to investigate the function of Caspase12 in various biological systems.