CD13 Polyclonal Antibody

Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.

The CD13 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of CD13 protein expression in various biological samples. This antibody is produced through a rigorous process of immunization and purification, ensuring its high affinity and specificity towards CD13.

With its exceptional performance, this antibody enables researchers to investigate the role of CD13 in various cellular processes, including cell adhesion, migration, and differentiation. It is suitable for use in a wide range of applications, such as immunohistochemistry, immunofluorescence, and western blotting.

The CD13 Polyclonal Antibody exhibits minimal cross-reactivity with other antigens, ensuring accurate and reliable results. Its superior sensitivity allows for the detection of low levels of CD13 expression, making it an ideal choice for both qualitative and quantitative analysis.

This antibody is supplied in a convenient and ready-to-use format, eliminating the need for time-consuming preparation. It is available in various sizes to accommodate different experimental requirements.

Choose the CD13 Polyclonal Antibody for its exceptional performance, reliability, and versatility, and unlock new insights into the function and regulation of CD13 in biological systems.