CD45 Monoclonal Antibody(12A9)

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which enc

The CD45 Monoclonal Antibody (12A9) is a highly specific and reliable tool for immunohistochemistry and flow cytometry applications. This antibody is designed to target the CD45 antigen, a transmembrane protein expressed on all nucleated hematopoietic cells. With its exceptional sensitivity and specificity, the CD45 Monoclonal Antibody (12A9) enables accurate identification and characterization of leukocytes in various research and diagnostic settings.

This antibody is produced using advanced monoclonal antibody technology, ensuring batch-to-batch consistency and high purity. It has been extensively validated and optimized for use in immunohistochemistry and flow cytometry, providing consistent and reproducible results. The CD45 Monoclonal Antibody (12A9) exhibits minimal cross-reactivity with other antigens, minimizing the risk of false-positive or false-negative results.

In immunohistochemistry applications, the CD45 Monoclonal Antibody (12A9) demonstrates excellent staining performance on formalin-fixed, paraffin-embedded tissue sections. It offers clear and distinct staining of leukocytes, allowing for accurate identification and localization within the tissue. This antibody is compatible with various detection systems and can be used in combination with other antibodies for multiplex staining.

For flow cytometry applications, the CD45 Monoclonal Antibody (12A9) provides reliable and accurate identification of leukocyte populations in complex cell mixtures. It offers excellent signal-to-noise ratio and high sensitivity, enabling precise quantification and analysis of different leukocyte subsets. This antibody is compatible with a wide range of flow cytometry instruments and can be used with various fluorochrome-conjugated secondary antibodies for multiparameter analysis.

The CD45 Monoclonal Antibody (12A9) is supplied as a ready-to-use solution, eliminating the need for time-consuming antibody preparation. It is provided in a convenient format, allowing for easy and efficient handling. This antibody is stable and long-lasting, ensuring consistent performance over time.

In summary, the CD45 Monoclonal Antibody (12A9) is a highly specific and reliable tool for immunohistochemistry and flow cytometry applications. With its exceptional sensitivity, specificity, and ease of use, this antibody is an essential component for accurate leukocyte identification and characterization in research and diagnostic settings.