Cdk9 (Acetyl Lys44) Rabbit Polyclonal Antibody

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28| and S. pombe cdc2| and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb| which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T| which suggested a possible involvement of this protein in AIDS.

The Cdk9 (Acetyl Lys44) Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Cdk9 protein in various biological samples. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring excellent performance and reliability.

Cdk9, also known as cyclin-dependent kinase 9, plays a crucial role in cell cycle regulation and transcriptional control. It is involved in the regulation of RNA polymerase II transcription elongation and is a key component of the positive transcription elongation factor b (P-TEFb) complex. The acetylation of Lys44 in Cdk9 has been shown to be important for its kinase activity and transcriptional regulation.

The Cdk9 (Acetyl Lys44) Rabbit Polyclonal Antibody has been extensively validated for its specificity and sensitivity. It exhibits minimal cross-reactivity with other related proteins, ensuring accurate and reliable results. This antibody is suitable for various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

With its high affinity and specificity, the Cdk9 (Acetyl Lys44) Rabbit Polyclonal Antibody is an essential tool for researchers studying cell cycle regulation, transcriptional control, and related fields. Its reliable performance and consistent results make it an ideal choice for both basic research and clinical applications.