CEAM6 Polyclonal Antibody

This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19.

The CEAM6 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of CEAM6 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of the human CEAM6 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards CEAM6, making it an ideal tool for various applications such as Western blotting, immunohistochemistry, and ELISA.

The CEAM6 Polyclonal Antibody is purified using a combination of protein A and protein G chromatography, ensuring high purity and minimal cross-reactivity with other proteins. This antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is recommended to store the antibody at -20°C for long-term storage and avoid repeated freeze-thaw cycles.

The CEAM6 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications. It has been shown to detect CEAM6 protein in various human tissues, including colon, lung, and breast cancer tissues. This antibody has also been used to study the role of CEAM6 in cancer progression and metastasis.

In summary, the CEAM6 Polyclonal Antibody is a reliable and high-quality reagent for the detection and quantification of CEAM6 protein in various biological samples. Its high specificity and sensitivity make it an ideal tool for various applications in research and diagnostics.