Chk1(Phospho Ser286) Polyclonal Antibody

The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.

The CHK1(PHOSPHO SER286) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of CHK1 protein phosphorylated at serine 286. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional sensitivity and specificity in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The CHK1(PHOSPHO SER286) Polyclonal Antibody exhibits excellent performance in detecting the phosphorylation status of CHK1 at serine 286, a critical site involved in the regulation of cell cycle progression and DNA damage response. With its high affinity and selectivity, this antibody enables accurate and precise quantification of CHK1 phosphorylation levels, facilitating comprehensive investigations into cellular signaling pathways and molecular mechanisms.

This antibody is meticulously manufactured using state-of-the-art techniques, resulting in a highly purified and concentrated product. Its exceptional quality ensures minimal background noise and maximum signal intensity, allowing for reliable and reproducible experimental results. Furthermore, the CHK1(PHOSPHO SER286) Polyclonal Antibody demonstrates excellent stability and long shelf life, ensuring consistent performance over time.

In summary, the CHK1(PHOSPHO SER286) Polyclonal Antibody is an indispensable tool for researchers and scientists involved in the study of cell cycle regulation, DNA damage response, and related fields. Its exceptional specificity, sensitivity, and reliability make it an ideal choice for a wide range of applications, providing valuable insights into the intricate mechanisms governing cellular processes.