CIDE-B Polyclonal Antibody

Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes and bone marrow.

Introducing the CIDE-B Polyclonal Antibody, a cutting-edge scientific tool designed to facilitate advanced research in the field of cellular apoptosis. This meticulously developed antibody is specifically designed to target and detect the CIDE-B protein, a crucial regulator of programmed cell death.

Crafted with utmost precision and utilizing state-of-the-art technology, the CIDE-B Polyclonal Antibody offers exceptional sensitivity and specificity, ensuring accurate and reliable results. Its high affinity for the CIDE-B protein enables researchers to effectively investigate its role in various cellular processes, including lipid metabolism, obesity, and cancer.

The CIDE-B Polyclonal Antibody boasts an extensive range of applications, making it an invaluable asset in diverse experimental settings. Whether employed in Western blotting, immunohistochemistry, or immunofluorescence assays, this antibody consistently delivers exceptional performance, enabling researchers to delve deeper into the intricate mechanisms underlying cellular apoptosis.

With its robust and reproducible results, the CIDE-B Polyclonal Antibody is an indispensable tool for scientists and researchers seeking to unravel the complexities of programmed cell death. Its unparalleled quality and reliability make it an ideal choice for laboratories and institutions at the forefront of biomedical research.

Invest in the CIDE-B Polyclonal Antibody today and unlock new avenues of discovery in the realm of cellular apoptosis. Experience the power of cutting-edge technology and elevate your research to unprecedented heights.