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ELK Biotechnology

SKU(재고 관리 코드):ES8637

CKR-5 Rabbit Polyclonal Antibody

CKR-5 Rabbit Polyclonal Antibody

Size

CKR-5 Rabbit Polyclonal Antibody

Overview

Product name: CKR-5 rabbit pAb
Alternative Names: C-C chemokine receptor type 5 (C-C CKR-5;CC-CKR-5;CCR-5;CCR5;CHEMR13;HIV-1 fusion coreceptor;CD antigen CD195)
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 151-200
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 40kD
GeneID(Human): 1234
Human Swiss-Prot No: P51681
Cellular localization: Cell membrane ; Multi-pass membrane protein .
Background: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemok
Species Reactivity: Human;Rat;Mouse;
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