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ELK Biotechnology
SKU(재고 관리 코드):ES8637
CKR-5 Rabbit Polyclonal Antibody
CKR-5 Rabbit Polyclonal Antibody
CKR-5 Rabbit Polyclonal Antibody
Overview
| Product name: | CKR-5 rabbit pAb |
| Alternative Names: | C-C chemokine receptor type 5 (C-C CKR-5;CC-CKR-5;CCR-5;CCR5;CHEMR13;HIV-1 fusion coreceptor;CD antigen CD195) |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000 |
| Immunogen: | Synthetic peptide from human protein at AA range: 151-200 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 40kD |
| GeneID(Human): | 1234 |
| Human Swiss-Prot No: | P51681 |
| Cellular localization: | Cell membrane ; Multi-pass membrane protein . |
| Background: | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemok |
| Species Reactivity: | Human;Rat;Mouse; |
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Western blot analysis of 293T lysate, antibody was diluted at 2000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 -
Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200 -
Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200
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