Cleaved-Cathepsin C HC (R394) Polyclonal Antibody

CTSC encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. Cathepsin Crequires chloride ions for activity and can degrade glucagon. Defects in the cathepsin C have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.

The Cleaved-Cathepsin C HC (R394) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of cleaved cathepsin C HC (R394) in various biological samples. This antibody is produced using advanced techniques, ensuring high affinity and specificity towards the target protein.

Cathepsin C HC (R394) is a crucial enzyme involved in the activation of several serine proteases, playing a vital role in various physiological and pathological processes. The Cleaved-Cathepsin C HC (R394) Polyclonal Antibody recognizes the cleaved form of cathepsin C HC (R394), enabling researchers to investigate its activation and function in different cellular and tissue contexts.

This polyclonal antibody exhibits exceptional sensitivity, allowing for the detection of even low levels of cleaved cathepsin C HC (R394) in complex biological samples. It has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Cleaved-Cathepsin C HC (R394) Polyclonal Antibody is supplied as a ready-to-use solution, ensuring convenience and ease of use. It is provided in a vial with optimal storage conditions, maintaining its stability and activity for an extended period.

With its high specificity, sensitivity, and versatility, the Cleaved-Cathepsin C HC (R394) Polyclonal Antibody is an indispensable tool for researchers studying cathepsin C HC (R394) activation and its implications in various biological processes.